E-cigarette withdrawal symptoms
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E-Cigarette Withdrawal Symptoms: Prevalence and Severity
Research shows that withdrawal symptoms can occur when people stop using e-cigarettes, but the severity and type of symptoms can vary depending on user history, device type, and context. Both physical and psychological symptoms have been reported, though they are often less intense than those experienced with traditional tobacco cigarettes 23.
Physical and Psychological Withdrawal Symptoms
Common withdrawal symptoms from e-cigarette abstinence include cravings for e-cigarettes and tobacco cigarettes, mood swings, anxiety, impulsivity, and anhedonia (loss of pleasure) . Physical symptoms such as increased appetite and decreased heart rate have also been observed . In studies of users who stopped e-cigarettes during intermittent fasting, most reported only weak physical and psychological withdrawal symptoms .
Comparison to Tobacco Cigarette Withdrawal
The severity of withdrawal from e-cigarettes is generally somewhat less than that from daily tobacco cigarette use, but it is still significant enough to indicate physical dependence 23. Fewer e-cigarette users report withdrawal symptoms compared to tobacco cigarette users, and the symptoms tend to be milder . In dual users (those who use both e-cigarettes and tobacco cigarettes), continued tobacco use appears to reduce e-cigarette withdrawal symptoms, but not vice versa .
Withdrawal in Never-Smokers and Former Smokers
Even never-smokers who use e-cigarettes daily can experience withdrawal symptoms when they stop, though these symptoms are usually mild and may not be clinically significant . Former smokers who switch to daily e-cigarette use also show withdrawal symptoms upon cessation, indicating that dependence can transfer from tobacco to e-cigarettes .
Device Type and Withdrawal Symptom Relief
The type of e-cigarette device can influence withdrawal symptom relief. Second-generation e-cigarettes are more effective at reducing nicotine withdrawal symptoms than first-generation devices . Additionally, the visual appearance of the device can affect withdrawal and craving, especially for new users; devices that look more like traditional cigarettes may provide greater relief .
Cognitive and Affective Changes During Withdrawal
Withdrawal from e-cigarettes can lead to cognitive and affective changes, such as anxiety, depression, and memory deficits. These symptoms can persist or even appear late after stopping long-term e-cigarette use, as shown in animal studies . In humans, acute use of nicotine-containing e-cigarettes can improve working memory and reduce withdrawal symptoms, especially in males .
Interventions to Reduce Withdrawal Symptoms
Preliminary research suggests that cannabidiol (CBD) may help reduce the severity of nicotine withdrawal symptoms and anxiety during e-cigarette abstinence . Behavioral strategies, such as keeping busy, are also commonly used by individuals to manage withdrawal symptoms during periods of abstinence, such as intermittent fasting .
Conclusion
E-cigarette withdrawal symptoms are real and can include both physical and psychological effects, though they are often milder than those from tobacco cigarettes. The severity of symptoms depends on user history, device type, and context. Awareness of these symptoms and potential interventions, such as CBD or behavioral strategies, may help individuals manage withdrawal and support cessation efforts.
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Most relevant research papers on this topic
Electronic cigarettes’ withdrawal severity symptoms among users during intermittent fasting: a cross-sectional study
E-cigs may help smokers quit during intermittent fasting, as their physical and psychological withdrawal symptoms are relatively weak.
Withdrawal Symptoms From E-Cigarette Abstinence Among Former Smokers: A Pre-Post Clinical Trial.
E-cigarette use can maintain physical dependence in former smokers, with withdrawal symptoms being slightly less severe than those from daily tobacco cigarette use.
DOI
The comparative efficacy of first- versus second-generation electronic cigarettes in reducing symptoms of nicotine withdrawal.
Second-generation e-cigarettes are more effective in reducing nicotine withdrawal symptoms than first-generation e-cigarettes.
Withdrawal Symptoms from E-Cigarette Abstinence Among Adult Never-Smokers: A Pilot Experimental Study.
Never-smokers can experience small withdrawal symptoms from abruptly stopping e-cigarettes, but the severity is not clinical or regulatory significance.
DOI
Cannabidiol Reduces Nicotine Withdrawal Severity and State Anxiety During an Acute E-cigarette Abstinence Period: A Novel, Open-Label Study
CBD reduces nicotine withdrawal severity and state anxiety during e-cigarette abstinence, potentially aiding in e-cigarette quit attempts.
The Effects of E-Cigarette Visual Appearance on Craving and Withdrawal Symptoms in Abstinent Smokers
Cigarette-like appearance in e-cigarettes is associated with lower craving and withdrawal symptoms in abstinent smokers, but only for those with no prior e-cigarette experience.
DOI