Psoriasis and Lupus Erythematosus—Similarities and Differences between Two Autoimmune Diseases

doi:10.3390/jcm13154361

Paper

Psoriasis and Lupus Erythematosus—Similarities and Differences between Two Autoimmune Diseases

Published Jul 25, 2024 · Aleksandra Fijałkowska, Joanna Wojtania, A. Woźniacka

Journal of Clinical Medicine

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Abstract

Systemic lupus erythematosus (SLE) and psoriasis (Ps) are two clinically distinct diseases with different pathogenesis. However, recent studies indicate some similarities in both clinical presentation and pathogenetic mechanisms. The coexistence of both entities is very uncommon and has not been fully elucidated. Thus, it remains a diagnostic and therapeutic challenge. In fact, drugs used in SLE can induce psoriatic lesions, whereas phototherapy effective in Ps is an important factor provoking skin lesions in patients with SLE. The aim of this work is to discuss in detail the common pathogenetic elements and the therapeutic options effective in both diseases.

Study Snapshot

Psoriasis and lupus erythematosus share some similarities in clinical presentation and pathogenetic mechanisms, but their coexistence is uncommon and requires further investigation.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Psoriasis and Lupus Erythematosus—Similarities and Differences between Two Autoimmune Diseases

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