Paper

Progressive plasticity during colorectal cancer metastasis

Published Oct 30, 2024 · Andrew Moorman, Elizabeth K. Benitez, Francesco Cambulli

Nature

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Abstract

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In Vitro Study

Study Snapshot

Colorectal cancer metastases display progressive plasticity, reprogramming into fetal progenitor states and undergoing non-canonical differentiation, which is linked to poor patient survival and therapy resistance.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Progressive plasticity during colorectal cancer metastasis

References

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