Paper
Herpes Virus Type 6
Published May 4, 2019 · Orinthia King, Y. Khalili
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Abstract
Human herpesvirus 6 (HHV-6) was initially discovered in blood lymphocytes of adults with lymphoproliferative diseases or AIDS and was labeled human B-lymphotropic virus. Further research identified HHV-6 in CD4+ lymphocytes and as a member of the herpesviruses. As it was the sixth herpesvirus isolated, it was then subsequently renamed human herpesvirus 6. Typical of a herpes virus, HHV-6 has been known to establish acute, incessant and permanent infection. HHV-6 is the collective name for the double-stranded DNA viruses HHV-6A and HHV-6B. HHV-6A and HHV-6B, are officially recognized as distinct viruses instead of variants within the herpesvirus family. While much less is known about HHV-6A, it occurs more frequently in the immunocompromised host. In contrast, research has identified HHV-6B as the etiologic agent of the childhood illness exanthema subitem (roseola infantum).[1] Acquisition of HHV-6B is quite common in the young and is frequently seen throughout emergency departments worldwide. HHV-6B is a ubiquitous virus, with over 90% of the human population infected within the first 3 years of life.
Human herpesvirus 6 (HHV-6) is a herpesvirus that causes acute, incessant, and permanent infections, with HHV-6A more common in immunocompromised hosts and HHV-6B being a ubiquitous virus that infects over 90% of the human population within the first 3 years
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