Paper

Frictiotaxis underlies focal adhesion-independent durotaxis

Published Apr 23, 2025 · Adam Shellard, Kai Weißenbruch, Peter A E Hampshire

Nature Communications

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

Cells can perform durotaxis despite lacking focal adhesions, guiding their migration towards regions of higher friction, potentially impacting development, immune response, and cancer progression.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Frictiotaxis underlies focal adhesion-independent durotaxis

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