Paper

HIF Regulates Multiple Translated Endogenous Retroviruses: Implications for Cancer Immunotherapy

Published Feb 1, 2025 · Qinqin Jiang, D. Braun, Karl R Clauser

Cell

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Abstract

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Case Report

Study Snapshot

HIF-induced endogenous retroviruses (ERVs) can be leveraged for cancer immunotherapy by generating antigen-specific T cell responses in clear cell renal cell carcinoma.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

HIF Regulates Multiple Translated Endogenous Retroviruses: Implications for Cancer Immunotherapy

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