Paper
A Particular Separation Method Development and Validation of Nadolol and Bendroflumethiazide by using RP-HPLC
Published Dec 25, 2023 · S. Sumaltha, D. Bharathi, Ramana Tamminana
INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE
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Abstract
We have developed a simple, general, and reliable HPLC Method and validation for the simultaneous estimation of nadolol and bendroflumethiazide drugs according to (ICH) guidelines. Nadolol and bendroflumethiazide peaks have been observed at a retention time of 1.757, and 3.208 minutes, respectively, and they have kept 5 minutes as a total run time. As per linearity results, the average correlation coefficient of nadolol and bendroflumethiazide is 0.999 which indicates they have good linearity, robustness, and stability.
A simple, reliable HPLC method has been developed for simultaneous estimation of nadolol and bendroflumethiazide, with good linearity, robustness, and stability.
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